As hemp and cannabis products continue to gain popularity for wellness and relief, it’s important to understand how they may interact with certain prescription medications. While CBD and other cannabinoids are natural compounds, they can still affect how your body processes some drugs, especially those metabolized by the liver.
At 502 Hemp, we want our customers to have the safest, most effective experience possible. Our team is here to help you make informed decisions and find products that work best for your needs.
When to Talk with a Professional
If you take prescription medications, blood thinners, sedatives, opioids, anticonvulsants, or antidepressants, it’s a good idea to consult your doctor or pharmacist before using cannabis or CBD. These substances can alter how your medications work or increase side effects.
Our 502 Hemp experts can help guide you through what to ask your provider and how to choose hemp products safely.
Common Drug Categories with Potential Interactions
1. Sedatives and Benzodiazepines
Examples: Alprazolam (Xanax), Diazepam (Valium), Lorazepam (Ativan)
Possible Interaction: Increased drowsiness or respiratory depression.
Using cannabis or CBD alongside sedatives can heighten their relaxing effects — sometimes too much. If you’re using these medications, always check with your healthcare provider first.
2. Opioids
Examples: Oxycodone, Hydrocodone, Morphine
Possible Interaction: Greater risk of sedation and slowed breathing.
While many people explore CBD for pain relief, combining it with opioids without guidance can be risky. Our knowledgeable staff can help you discuss safer options to support your comfort and wellness goals.
3. Antidepressants and Antipsychotics
Examples: Fluoxetine (Prozac), Sertraline (Zoloft), Quetiapine (Seroquel), Aripiprazole (Abilify)
Possible Interaction: Altered medication levels or increased side effects.
CBD and THC can influence how the liver breaks down these drugs, changing how they act in your system. Talking with a medical professional is key before mixing these.
4. Anticonvulsants
Examples: Clobazam, Valproate, Carbamazepine
Possible Interaction: CBD may change how seizure medications work in your body.
If you use CBD for neurological support, it’s especially important to coordinate with your healthcare team.
Quick Actions You Can Take
- Ask your pharmacist to run a cannabis/CBD interaction check on your current prescriptions.
- Scan the QR code below to view a Major Drug Interactions with Cannabis list.
- Talk with the experts at 502 Hemp, we’re always happy to answer questions, share research, and help you find products that fit your wellness routine safely.
Shop Smart. Stay Safe. Feel Better.
At 502 Hemp, our goal is to empower you with trustworthy education and premium hemp products. Whether you’re new to CBD or a long-time user, our knowledgeable team is here to help you make confident, informed choices.
Visit us in-store or shop online at 502Hemp.com to explore safe, lab-tested hemp products, and let us help you find what works best for your wellness journey.
This blog is not intended to be used as medical advice. We are not medical professionals. Always check with your doctors before using any supplements.